Anion and cation permeability of a chloride channel in rat hippocampal neurons.
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چکیده
منابع مشابه
Anion and cation permeability of a chloride channel in rat hippocampal neurons
The ionic permeability of a voltage-dependent Cl channel of rat hippocampal neurons was studied with the patch-clamp method. The unitary conductance of this channel was approximately 30 pS in symmetrical 150 mM NaCl saline. Reversal potentials interpreted in terms of the Goldman-Hodgkin-Katz voltage equation indicate a Cl:Na permeability ratio of approximately 5:1 for conditions where there is ...
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I N T R O D U C T I O N This article examines the ionic selectivity o f an anion channel that is consistently found in the somatic membran e o f hippocampal neurons f rom embryonic rats. Characteristic o f the channel is a relatively small unitary conductance (~30 pS in symmetrical 150 mM NaCI saline) that is tu rned on and of f by a weakly voltage-dependent , kinetically complex gating process...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1987
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.90.4.453